| Theme | Imagination and Evaluation of the Dialysis Dose | |
|---|---|---|
| Title | Dialysis dose in terms of small solutes volume | |
| Publish Date | 2003/09 | |
| Author | Masahiro Goto | Division of Blood Purification, Mihama Hospital |
| Author | Toshio Takeda | Division of Blood Purification, Mihama Hospital |
| Author | Junji Uchino | Division of Blood Purification, Mihama Hospital |
| Author | Takashi Kouno | Department of Urology, Mihama Hospital |
| Author | Toyohiko Yoshida | Department of Urology, Mihama Hospital |
| [ Summary ] | The index showing removal efficiency and generation rates is obtained by changes in solutes concentrations of urea nitrogen (UN) and creatinine (Cr) in the blood over a week long period with hemodialysis patients. This change in solute concentration and various indices are all useful to evaluate dialysis dose. In the post-dialysis period the solute concentrations became lowest over the weekends, as measured by tests three times per week, UN was below normal values in about 85% of the cases, however, most of the Cr levels were beyond normal values. The dialysis dose can not be determined only by evaluation of UN. Estimations made by using Kt/V of Cr, with an average clearance rate within a week were about 15l/day, dialysis dose is not adequate in terms of small solutes. Therefore, it is important to set up dialysis conditions, check patients condition and consider removal and generation as well as maintaining the present dialysis dose, in order to make further treatment improvements. | |