| Theme | Intoxication of Drugs and Poisons and Blood Purification Therapy (Case Report) | |
|---|---|---|
| Title | Therapy for cresol poisoning | |
| Publish Date | 2002/07 | |
| Author | Tatsuya Tsujito | Department of Anesthesiology and Critical Care Medicine, Gifu University School of Medicine |
| Author | Shuji Dohi | Department of Anesthesiology and Critical Care Medicine, Gifu University School of Medicine |
| [ Summary ] | Cresol, a phenol derivative (CH3C6H4OH), has been widely used for disinfecting inanimate objects. Since its disinfectant effects are due to denaturation and precipitation of proteins, cresol is extremely destructive to tissue of the mucous membrane, upper respiratory tract, eyes, and skin. Cresol intoxication can develop either after inhalation, cutaneous absorption, or oral ingestion and may result in respiratory failure, renal dysfunction, and/or coma in severe cases. No report, however, has described cresol ingestion causing marked increases in aminotransferase levels. We present a case of a 26-year-old woman whose aminotransferase levels markedly increased 24 hours after ingestion of 70ml of cresol. She received no specific therapy, or blood purification, and recovered without neurological complications. |
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