The Japanese Journal of Clinical Dialysis Vol.18 No.2(6)

Theme Sleep Apnea Syndrome in Maintenance Hemodialysis Patients
Title Chronic respiratory diseases and SAS
Publish Date 2002/02
Author Wataru Hida Department of Informatics on Pathophysiology, Tohoku University Graduate School of Information Sciences
Author Manami Oikawa Department of Respiratory & Infectious Diseases, Postgraduate Division, Tohoku University School of Medicine
[ Summary ] Since neither chronic respiratory diseases, such as chronic obstructive pulmonary disease (COPD), bronchial asthma and restrictive ventilatory impairment nor sleep apnea syndrome (SAS) is rare, COPD and SAS can occasionally coexist. An association of these two diseases has relatively profound nocturnal hypoxemia, compared with each alone, and also leads to the development of right ventricular failure, so-called cor pulmonale. Continuous positive airway pressure (CPAP) or non-invasive positive pressure ventilation (NPPV) is useful for treatment of SAS. However, even though CPAP or NPPV has improved apnea/hypopnea episodes associated with SAS, some patients still display nocturnal hypoxemia. For treatment of such patients, the combination of CPAP or NPPV and supplemental oxygen therapy should be made available.
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