| [ Summary ] |
Appetite loss, nausea and vomiting are frequently seen in end stage renal disease (ESRD). These symptoms induce further renal deterioration through dehydration, hyponatremia and metabolic acidosis, which results in need for initiation of dialysis therapy. They are originated from not only gastrointestinal tract disease but also other organ abnormalities. In patients recieving dialysis, the therapy or drug-induced disease must be ruled out as a cause of these symptoms. Serum amylase, transaminases and some tumor-markers are out of normal ranges in dialysis patients. There are many drugs which are contraindicated or which require dose reduction. Careful observation must be done in diagnosis and treatment of digestive disease in patient with ESRD. |