The Japanese Journal of Clinical Dialysis Vol.17 No.6(4)

Theme Malignancy in Chronic Renal Failure
Title ACDK and renal cell carcinoma
Publish Date 2001/06
Author Isao Ishikawa Division of Nephrology, Department of Internal Medicine, Kanazawa Medical University
[ Summary ] 1) The incidence of renal cell carcinoma is high in patients with chronic renal failure and also in dialysis patients, compared to the general population. The 80% of renal cell carcinomas in dialysis patients were related to acquired renal cysts (ACDK). The reason why the incidence of renal cell carcinoma is high in dialysis patients, is that renal cell carcinoma develops in relation to ACDK. There is a close relationship between renal cell carcinoma and ACDK: renal cysts derive from the renal tubules, cystic epithelial cells proliferate, and renal cell carcinomas also develop. Accordingly, renal cell carcinoma increases in long-term dialysis patients.
2) Because of the incidence of renal cell carcinoma in dialysis patients is high and there are no symptoms, screening is important, especially for high risk patients.
3) If an echogenic mass, found through ultrasonic examination or a mass with a parenchymal absorption value is found with CT scanning blood flow inside the tumor should be proven by any method possible before an operation is performed.
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