| Theme | Malignancy in Chronic Renal Failure | |
|---|---|---|
| Title | Malignant tumors in chronic dialysis patients -- Review of foreign literature | |
| Publish Date | 2001/06 | |
| Author | Seiji Ohira | Department of Surgey and Kidney Center, Nikko Memorial Hospital |
| Author | Noritomo Itami | Department of Surgey and Kidney Center, Nikko Memorial Hospital |
| Author | Yasushige Tsuji | Department of Surgey and Kidney Center, Nikko Memorial Hospital |
| [ Summary ] | There are many papers which report a higher incidence of malignant tumors in the chronic dialysis population compared to general population. In this review, the foreign situation was investigated with the paper of Maisonneuve et al. (Lancet 354: 93-99, 1999) as the central basis. Chronic dialysis patients, in general, have a relatively high cancer risk, with the greatest number of cancers being discovered within the first year after initiating dialysis. It is highly possible that the predialytic uremic condition is a related carcinogenic factor. In one type of renal cancer, the incidence rate increases the longer dialysis treatment continues and one must wonder if long term dialysis itself has influence on the carcinogenesis. One surprising observation is the extremely high risk of cancer in the younger group of dialysis patients (<35 years). As the cases analyzed by Maisonneuve et al differed in several aspects from those in Japan, we must be careful when applying their results to our own cases. There is an urgent need for this type of data to be collected and analyzed in Japan, which now takes care of about 200,000 dialysis patients. |
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