| Theme | Adequate Dialysis : Current Topics in Kinetic Modeling | |
|---|---|---|
| Title | Beta2-microglobulin kinetics during hemodialysis | |
| Publish Date | 2001/04 | |
| Author | Masamiki Miwa | Department of Internal Medicine, Nagoya University Daiko Medical Center |
| Author | Takahiro Shinzato | Department of Internal Medicine, Nagoya University Daiko Medical Center |
| [ Summary ] | On the basis of the three-pool beta2-microglobulin (beta2-m) kinetic model by Odell and co-workers, we devised equations, by which beta2-m Kt/V may be calculated. When the beta2-m removal amount was fixed at 7mg/kg, the Kt/V value was virtually constant as dialyzer clearance of beta2-m incresed, whereas the beta2-m reduction rate increased as the dialyzer clearance of beta2-m increased. These findings may be due to the fact that the rebound of plasma beta2-m concentration was taken into account when the Kt/V was calculated. |
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