| Theme | Management of Systemic Diseases with Blood Purification : Aute and Chronic Stage of Diseases | |
|---|---|---|
| Title | TTP (HUS) | |
| Publish Date | 2001/03 | |
| Author | Katsumi Ito | Department of Pediatric Nephrology, Tokyo Women's Medical University |
| Author | Toshiaki Suzuki | Department of Pediatric Nephrology, Tokyo Women's Medical University |
| Author | Motoshi Hattori | Department of Pediatric Nephrology, Tokyo Women's Medical University |
| [ Summary ] | Thrombotic thrombocytopenic purpura(TTP), typical diarrhea-associated (D+) hemolytic uremic syndrome (HUS), and atypical D-HUS have common pathological findings characterized by thrombotic microan giopathy; however, theses disease manifest different clinical features and outcome. Moreover, recent works have given rationale of fresh frozen plasma (FFP) infusions and plasma exchange (PE) for treatment of patients with TTP and atypical D-HUS. By contrast, patients with D+HUS have been treated with FFP infusions and PE with no apparent benefit. In this paper, we briefly reviewed PE therapy for patients with TTP and HUS. | |