| Theme | Expanding Clinical Experimental Findings for Nutritional Management | |
|---|---|---|
| Title | Nutritional status evaluations of protein metabolism among chronic dialysis patients : from the aspects of Kt/V, protein catabolic rate, creatinine height index, and serum albumin or creatinine concentrations | |
| Publish Date | 2001/11 | |
| Author | Eikichi Watanabe | Kidney Center, Shinraku-en Hospital |
| Author | Masashi Suzuki | Kidney Center, Shinraku-en Hospital |
| Author | Yoshihei Hirasawa | Kidney Center, Shinraku-en Hospital |
| [ Summary ] | A state of protein manutrition has frequently been recognized in approximately half of all chronic dialysis patients. For example, deceased serum protein levels evaluated by low serum albumin(Alb) concentrations, decreased muscle protein mass through low serum creatinin(Cr) levels, low creatinine generation rates(CGR), a creatinine height index(%CHI), as well as decreased dietary protein intake along with low protein catabolic rates(dPCR). These parameters have overt correlations with each other. Furthermore, dPCR has positive correlations to predialysis serum Cr, Alb, phosphate(P), potassium(K) levels and Kt/V. In spite of the improved dialysis efficiency, decreased dPCR, %CHI, Cr, Alb and transferrin(TF) are commonly seen in aged patients. Protein malnutrition parameters have been reported to be close predictors of poor prognoses. It is very important to maintain appropriate visceral protein parameters. Therfore, prevention and amendment of protein malnutrition is necessary for prolonged patient' survival. |
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