| Theme | Forefront of Diabetic Nephropathy | |
|---|---|---|
| Title | Insulin secretion -- Recent topics | |
| Publish Date | 2001/01 | |
| Author | Yoshihiko Sato | Department of Aging Medicine and Geriatrics, Shinsyu University School of Medicine |
| Author | Mitsuhisa Komatsu | Department of Aging Medicine and Geriatrics, Shinsyu University School of Medicine |
| Author | Tohru Aizawa | Department of Aging Medicine and Geriatrics, Shinsyu University School of Medicine |
| Author | Kiyoshi Hashizume | Department of Aging Medicine and Geriatrics, Shinsyu University School of Medicine |
| [ Summary ] | The mechanism of glucose-induced insulin secretion from pancreatic beta-cells remains to be established. One well established pathway is the "ionic branch" which involves ATP sensitive K channels and calcium influx. We discovered the "non-ionic branch" of glucose-induced insulin secretion, and searched for possible candidates related to this mechanisms. Newer technologies enables us to find novel aspects of the insulin secretion mechanism. |
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