| Theme | Dialysis Therapy and Carnitine | |
|---|---|---|
| Title | Physiological aspect of carnitine | |
| Publish Date | 2000/02 | |
| Author | Kenji Maeda | Department of Internal Medicine, Nagoya University Daiko Medical Center |
| [ Summary ] | Carnitine plays an essential role as a carrier in the transport of Iong-chain fatty acids through the inner mitochondrial membrane. When there are deficiencies in levels of carnitine, cardiac function diminishes, protein catabolic rates in muscles are accelerated, and anemia and hyperlipideinia are promoted. In the normal kidney, excess carnitine or components of the acyl group can he excreted into the urine via acylcarnitine, which is the metabolic product of carnitine adjustment. In chronic dialysis patients, carnitine deficiency is apt to occur. Lamb and beef products contain high levels of carnitine. Thus, care most be taken when eating such foods to assure carnitine replenishment. It is important to eat properly so that this kind of deficiency does not continue for the long term. |
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