The Japanese Journal of Clinical Dialysis Vol.16 No.14(11)

Theme CAPD Up-to-date 2000
Title Nutritional management on CAPD patients
Publish Date 2000/12
Author Shigeko Hara Kidney Center of Toranomon Hospital
[ Summary ] Malnutrition of long-term and aged dialysis patients, is a major problem, because disturbance of QOL and poor prognoses.
A nutritional assessment was done for 45 cases of CAPD. BMI showed normal ranges in a patients. The values of BMI and serum alubumin levels gradualy increased after the start of dialysis therapy. However, over ten years on duration of dialysis the value of BMI, and albumin levels decreased. Over a ten year, period, levels of malnutrition in CAPD cases became apparent. Significantly, there was a negative correlation between age and IGF-1. Albumin levels were also observed in these patients.
For management of states of malnutrition, adequent dialysis and diet therapy are applied for patients. Application of GH therapy has recently been reported for malnourished CAPD patients. In cases of underdialysis, changes to hemodialysis or combination therapy with hemodialysis, are nessesary.
The elevation of IGF-1 levels is induced by the infusion of Arginine, and malnutritional states. Amino acid containg dialysate for CAPD, showed the improvements in Aminograms but complications of acidosis were observed.
Further investigation is nesessary for management of malnutrition in CAPD cases.
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