The Japanese Journal of Clinical Dialysis Vol.15 No.8(9)

Theme Bone Fracture in Patients with Renal Replacement Therapy
Title Technical management during hemodialysis therapy on patients with bone fracture
Publish Date 1999/07
Author
Author
[ Summary ] The number of aged and long-term hemodialysis patients is increasing, and the number of cases with complications due to bone fractures is also increasing. In this paper we summarize technical management to avoid the risk of progression of bleeding by using heparin or anticoagulants during dialysis therapy.
The key point in management is a strategy for control of bleeding at the onset, before and/or after the operation. Technical devices and or medications are used. Partial blood circulation system on the blood circuit, non heparinization nafamostat mesilate and low molecular weight are used when there is a risk of bleeding. Whole blood coagulatuion time is lengthened under treatment with low molecular weight haparin.
Moreover, hyperpottasemia and high nitrogen value due to hamatoma and acidosis are frequently observed. Adequate dialysis therapy is nessesary to control renal failure.
On cranial bone fractures, management to prevent brain edema is important. Occasionaly, continuous dialysisis better than intermittent dialysis therapy for control of brain edema. HF (hemofiltration), CHD, CHDT and CAPD are also applied. Constant infusion of Glycerol is used during hemodialysis therapy to preserve serum osmolarity.
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