| Theme | Apheresis | |
|---|---|---|
| Title | Organ transplantation and apheresis | |
| Publish Date | 1999/06 | |
| Author | Shinichi Nishi | Department of Blood Purification Center, Niigata University |
| Author | Susumu Hasegawa | Department of Blood Purification Center, Niigata University |
| Author | Iku Sakata | Second Department of Internal Medicine, School of Medicine, Niigata University |
| Author | Hajime Yamazaki | Second Department of Internal Medicine, School of Medicine, Niigata University |
| Author | Kazuhide Saito | Department of Urology, School of Medicine, Niigata University |
| Author | Kouta Takahashi | Department of Urology, School of Medicine, Niigata University |
| [ Summary ] | Apheresis is one of the blood purification methods used to remove pathogenic factors from circulating blood. In organ transplantation, apheresis is used as a supporting method to help the success of organ transplantations, such as those of livers and kidnies. In order to utilize limited numbers of donors as well as possible, ABO incompatible renal transplantation is expanding in our country. This is because removing anti A or B antibodies through apheresis can inhibit severe acute rejections caused by ABO incompatible transplantation. Apheresis, that can remove vascular permeability factors from circulating blood, is also effective to reduce the incidence of recurrent focal glomerulosclerosis (FGS) after renal transplantation and to maintain high graft survival rates. | |