The Japanese Journal of Clinical Dialysis Vol.15 No.6(2-2)

Theme Apheresis
Title Apheresis for collagen disease
Publish Date 1999/06
Author Hiroshi Tsuda Department of Rheumatology, Juntendo University School of Medicine
Author Yoshinori Kanai Department of Rheumatology, Juntendo University School of Medicine
Author Yukihiro Matsuda Department of Rheumatology, Juntendo University School of Medicine
Author Yoshinari Takasaki Department of Rheumatology, Juntendo University School of Medicine
Author Hiroshi Hashimoto Department of Rheumatology, Juntendo University School of Medicine
[ Summary ] Recently plasmapheresis (PP) has been used for treatment of collagen related disease. Since 1980, PP has mainly been used for treatment of rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). When conducting PP, autoantibodies and immune complex components are removed. The indications for use of plasmapheresis are as follows (1) those which are resistent to some medications, (2) those which have a high quantity of antibodies or immune complex components, (3) those for which medication must be decreased or stopped because of side effects or complications, or (4) those which are in the acute active phase. We suggest DFPP may be useful as a treatment for collagen related disease.
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