The Japanese Journal of Clinical Dialysis Vol.15 No.5(9)

Theme Monitoring Technologies in Dialysis Therapy
Title Development of a creatinine monitoring system in the effluent dialysate
Publish Date 1999/05
Author Hideo Ebisawa Department of Clinical Engineering, Kidney Center, Tokyo Women's Medical University
Author Jun Murakami Department of Clinical Engineering, Kidney Center, Tokyo Women's Medical University
Author Iwakazu Kaneko Department of Clinical Engineering, Kidney Center, Tokyo Women's Medical University
Author Michio Mineshima Department of Surgery III, Kidney Center, Tokyo Women's Medical University
Author Tetsuzo Agishi Department of Surgery III, Kidney Center, Tokyo Women's Medical University
[ Summary ] A creatinine monitor has recently been introduced in order to establish optimal treatment for each patient. This monitor is based on a colorimetric method, using picric acid. The value of absorbance of the creatinine solution, involving picric acid, gradually increased and reached a maximum value 15 min after the introduction of picric acid to the sample of effluent dialysate. A favorable correlation between the maximum value and the estimated value from the absorbance data was obtained in 5 min. The creatinine monitoring system is thought to be useful for the establishment of adequate dialysis for each patient, especially in home hemodialysis.
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