| Theme | New Skin Care of Exit Site in CAPD | |
|---|---|---|
| Title | Exit-site infections in continuous ambulatory peritoneal dialysis patients | |
| Publish Date | 1997/05 | |
| Author | Satoshi Nakashio | Department of Internal Medicine and Laboratory Medicine, St. Marianna University School of Medicine |
| [ Summary ] | Exit-site infection and concomitant peritonitis have been the major complications and the most frequent cause of drop-out since continuous ambulatory peritoneal dialysis (CAPD) was introduced as an alternative for patients with end-stage renal failure. Gradual development in the innovation of catheters and devices to avoid ingress of microorganisms to the peritoneal cavity, at the intra-and periluminal level, was one of the elements that contributed to the morbidity and mortality of CAPD treatment. The use of medical devices has created serious problems related to nosocominal bacterial infections, since such devices are frequently colonized by various species of bacteria which form a biofilm. Within the biofilm glycocalyx, bacteria are shielded from antibiotics, antibodies and surfactants. Early diagnosis as well as early treatment of periluminal infection has the potential to decrease the frequency of peritonitis and exit-site infections. |
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