| Theme | Functional and Organic Changes of Brain Observed in Dialysis Patients | |
|---|---|---|
| Title | Recent trends in cerebrovascular diseases among hemodialysis patients | |
| Publish Date | 1997/02 | |
| Author | Masakuni Kameyama | Sumitomo Hospital, Section of Neurdogy Section of Hemodialysis |
| Author | Masaru Sakaguchi | Sumitomo Hospital, Section of Neurdogy Section of Hemodialysis |
| Author | Kazuto Nishinaka | Sumitomo Hospital, Section of Neurdogy Section of Hemodialysis |
| Author | Fukashi Udaka | Sumitomo Hospital, Section of Neurdogy Section of Hemodialysis |
| [ Summary ] | In chronic hemodiaiysis (HD) patients, massive cerebral hemorrhage was more common than cerebral infarction as a cause of death. We investigated the incidence of asymptomatic cerebral infarction (ACI), based on MRI findings, in 71 HD-outpatients with no past were normal in 32, cerebral white matter lesions were found in 25, basal ganglia infarcts in 25 and pontine history of cerebrovascular accidents in 8 patients. The rate of abnormal findings was significantly higher in older patients. Mean blood pressure after dialysis was significantly lower in patients with subcortical white matter and basal ganglia infarctions while in pontine lesions diastolic blood pressure was significantly lower and the level of serum HDL-cholesterol showed a significantly greater decrease. Depressive states and cognitive functions in these HD-ACI patients merit considerable attention. | |