The Japanese Journal of Clinical Dialysis Vol.13 No.13(2-2-1)

Theme Dialysis Therapy and Respiratory Systems
Title Respiratory function and blood gas analysis
Publish Date 1997/12
Author Yasushi Obase Second Department of Internal Medicine, Nagasaki University School of Medicine
Author Teruhumi Shimoda Second Department of Internal Medicine, Nagasaki University School of Medicine
Author Nobuko Matsuo Second Department of Internal Medicine, Nagasaki University School of Medicine
Author Shigeru Kohno Second Department of Internal Medicine, Nagasaki University School of Medicine
[ Summary ] Pulmonary function tests include measurement of lung volumes, flow-volume curve, mechanics, diffusing capacity and closing volume. Obstructive ventilatory impairment causes a decrease in FEV 1 %. Pulmonary emphysema manifests with an the elevation of RV, decreased diffusing capacity, and an increase in closing volume. Restrictive ventilatory impairment induced by lung disease is associated with a decrease in % VC.
Metabolic or respiratory acidosis and alkalosis can be determined by blood gas analysis. Anion gap(AG) is useful for estimating metabolic acidosis. Normal AG indicates renal dysfunction or diabetic ketoacidosis, and an increased AG indicates the reduction of HCO3-from the alimentary canal or renal tubular acidosis.
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