| [ Summary ] |
The mean arterial pressure of the healthy adult human is maintained at approximately 100mmHg. To maintain this pressure, various systems operate constantly in a well-integrated manner. The autonomic nervous system has a rapidly acting mechanism, which is important for blood pressure stability. Although its impairment leads to very unstable pressure, it is not thought to cause chronic hypertension. The hormonal factor represented by the renin-angiotensin system is an intermediate time-period pressure control mechanism, which is closely related to the long-term control of arterial pressure by the kidney.The long-term mechanism for arterial pressure regulation is closely associated with a basic role of the kidney, namely maintenance of body fluid and electrolyte homeostasis, which the pressure-natriuresis curve plays an important role. Therefore, involvement of the kidney would be necessary for long-term disturbance of blood pressure regulation, such as that seen in hypertension. |