| Theme | Colorectal cancer in ulcerative colitis | |
|---|---|---|
| Title | Radiographic features of dysplasia in ulcerative colitis | |
| Publish Date | 2005/01 | |
| Author | Takayuki Matsumoto | Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University |
| Author | Mitsuo Iida | Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University |
| [ Summary ] | Recent advances in endoscopic procedures, such as chromoscopy and magnifying colonoscopy, have contributed greatly to the diagnosis of dysplasia in ulcerative colitis (UC). However, positive results from of radiography in the detection of dysplasia have been poorly investigated. Thus, we retrospectively analyzed radiographic findings in neoplastic lesions found in 18 patients with UC. Gross radiographic and endoscopic findings were classified into categories having protrusions, flat visible lesions or stenosis. Out of 36 lesions detected with surveillance colonoscopy, 25 lesions (69 %) were found with subsequent radiography. Flat visible lesions were depicted as course or fine granular mucosa. However, flat visible lesions were less frequently depicted than protruding ones. The grade of dysplasia and the depth of invasion were no different between radiographically positive and negative lesions. Location in the distal colorectum and active ulcerative colitis were more frequent in radiographically negative lesions than in positive lesions. Our results indicate that radiography is not an alternative procedure to replace colonoscopy for surveillance in UC. However, it can depict a certain proportion of flat dysplasia. | |