INTESTINE Vol.7 No.6(1-1)

Theme Forefront of endoscopic treatment in early colorectal cancer
Title Injection solution
Publish Date 2003/11
Author Hironori Yamamoto Department of Internal Medicine, Division of Gastroenterology, Jichi Medical School
Author Osamu Tsuruta Department of Internal Medicine, Division of Gastroenterology, Jichi Medical School
Author Hiroto Kita Department of Internal Medicine, Division of Gastroenterology, Jichi Medical School
Author Michiko Iwamoto Department of Internal Medicine, Division of Gastroenterology, Jichi Medical School
Author Kentaro Sugano Department of Internal Medicine, Division of Gastroenterology, Jichi Medical School
[ Summary ] The submucosal dissection EMR method has attracted attention recently because it providesreliable en bloc resection of large superficial cancers of the GI tract. Although this method has been widely adopted for stomach lesions, it is still considered to be difficult to use for colonic lesions. It is important to select a long lasting injection solution, i.e. sodium hyaluronate, to perform the submucosal dissection EMR of colonic lesions. A submucosal injection of sodium hyaluronate thickens and hardens the soft thin colonic wall and it provides a safety margin for submucosal dissection.
The characteristics of sodium hyaluronate are presented as an injection solution for submucosal dissection EMR. The tips and pitfalls of this method are also described.
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