Theme | Non-neoplastic polys of the colon and rectum | |
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Title | Nonneoplastic colon polyps | |
Publish Date | 2002/09 | |
Author | Masahiro Ikegami | Department of Pathology, The Jikei University School of Medicine |
Author | Satoshi Nimura | Department of Pathology, The Jikei University School of Medicine |
Author | Hirohiko Kobayashi | Department of Pathology, The Jikei University School of Medicine |
Author | Tomoki Koyama | Department of Pathology, The Jikei University School of Medicine |
Author | Shoichi Saito | Third Department of Internal Medicine, Kyoto Prefectural University of Medicine |
Author | Hiroaki Sugisaka | First Department of Internal Medicine, The Jikei University School of Medicine |
Author | Hiroshi Hano | Department of Pathology, The Jikei University School of Medicine |
[ Summary ] | Proliferating cells of nonneoplastic polyps were localized at the lower zone of the crypts. In contrast, proliferating cells extended from the lower zone to the upper zone of the crypts in neoplastic polyps. Distribution of the proliferating cells was associated with a concentration of nuclei in HE staining. Therefore, to detect location in the concentrated nuclei, it was necessary to clarify the difference between neoplastic lesions and nonneoplastic lesions. We investigated nonneoplastic polyps, which were resected endoscopically. Most of the colon polyps were composed of tubular adenomas, intramucosal cancers and hyperplastic polyps. Under five percent of polyps displayed other nonneoplastic polyps historically. We described typical nonneoplastic polyps of the colon. We concluded it is necessary to collect many polyps resected by many medical institutions for further examination of nonneoplastic lesions excluding those related to hyperplastic polyps. |