| Theme | Average-risk colon cander screening | |
|---|---|---|
| Title | Comparison of clinicopathological findings of positive fecal occult blood test for colorectal cancers and symptomatic cancers | |
| Publish Date | 2001/03 | |
| Author | Koichi Koizumi | Department of Internal Medicine, Cancer Institute Hospital |
| Author | Yuzo Sakai | Department of Internal Medicine, Cancer Institute Hospital |
| Author | Shunkichi Kai | Department of Internal Medicine, Cancer Institute Hospital |
| Author | Masashi Ueno | Department of Surgery, Cancer Institute Hospital |
| Author | Hirotoshi Ohta | Department of Surgery, Cancer Institute Hospital |
| [ Summary ] | This study was a comparison of the results obtained from positive fecal occult blood tests for colorecal cancers (PFOBT), symptomatic cancers and colonoscopic ally screened asymptomatic cancers (CSA). One thousand two hundred and eight patients diagnosed and treated for colorectal cancer were examined. In the PFOBT group, there were one hundred eighty six cases. 37.3% were determined to have intramucosal carcinoma, and 14.2% were in the symptomatic group. The rates of stage 0,1 and 2, without lymphnode metastasis were 84.4% in the PFOBT group and 55.5% in the symptomatic group. Macroscopically, type 2 lesions (ulcerated type with clear margin) were most frequent in both groups. In cases of intramucosal cancer and submucosal cancer, the ratio of type 0-IIc and 0-IIc+IIa(superficial depressed type) were 1.6% with PFOBT, 9.9% in the symptomatic group and 7.1% for CSA. 24.3% of PFOBT, 31.5% of symptomatic cancer, 41.3% of CSA, were located the right side of the colon. The number of lesions 10mm or smaller was only 13.8%. The number less than 30mm was 73.9%, as seen in PFOBT. On the other hand, the number of lesions over 40mm in diameter was 53.8% for symptomatic cancers. Fecal occult blood tests may be useful to detect early stage colorectal cancer, although they are not so effective in finding find superficial depressed cancers, which have a tendency to infiltrate earlier. | |