INTESTINE Vol.25 No.4(8)

Series
Title Discontinuation of infliximab in patients with ulcerative colitis in remission (HAYABUSA): a multicentre, open-label, randomised controlled trial
Publish Date 2021/12
Author Eiji Harada Department of Gastroenterology, Akita Red Cross Hospital / Department of Gastroenterology, Tokushima Red Cross Hospital
Author Yoshihito Tanaka Department of Gastroenterology, Akita Red Cross Hospital / Department of Molecular Diagnostic Pathology, Iwate Medical University, School of Medicine
Author Hiro-o Matsushita Department of Gastroenterology, Akita Red Cross Hospital
Author Kenjiro Yoshikawa Department of Gastroenterology, Akita Red Cross Hospital
Author Ryo Takagi Department of Gastroenterology, Akita Red Cross Hospital
Author Bunichiro Kato
Author Shin Sasaki Department of Gastroenterology, Akita Red Cross Hospital
Author Hiroshi Hashimoto Department of Gastroenterology, Akita Red Cross Hospital
Author Tamotsu Sugai Department of Molecular Diagnostic Pathology, Iwate Medical University, School of Medicine
Author Noriyuki Uesugi Department of Molecular Diagnostic Pathology, Iwate Medical University, School of Medicine
Author Makoto Eizuka Department of Molecular Diagnostic Pathology, Iwate Medical University, School of Medicine
Author Hiro-o Yamano Department of Gastroenterology and Hepatology, Sapporo Medical University School of Medicine
[ Summary ] We present a case of carcinoma in sessile serrated adenoma/polyp based on Type II-like pit pattern with inconspicuous ductal dilatation. A follow-up colonoscopy was performed for a 70-year-old man. The patient presented with a Type IIa lesion (8mm in diameter) in the transverse colon. On magnifying chromoendoscopy, most parts of the lesions had a Type II-like pit pattern, characterized by inconspicuous dilatation and star-like findings. Moreover, some parts showed heterogeneity with a diameter of 2 mm; these parts were evaluated to be Type VI pit pattern. In addition, crystal violet staining recognized a small region where a slightly large and complicated star-like pit existed between the above two regions. We considered that a few serrated lesions had become malignant in most of their areas with changes in the atypia degree. The depth of invasion was classified as Tis. Endoscopic mucosal resection was performed. The pathological diagnosis was moderately differentiated adenocarcinoma (tub2) in sessile serrated adenoma/polyp; depth, pTis; Ly0; V0; pHM0; pVM0.
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