Theme |
An up-to-date review of the molecular-targeted therapies for inflammatory bowel disease |
Title |
Risk of coronavirus disease following targeted molecular therapy in patients with inflammatory bowel disease |
Publish Date |
2021/09 |
Author |
Hiroshi Nakase |
Department of Gastroenterology and Hepatology, Sapporo Medical University School of Medicine |
[ Summary ] |
Optimal management of patients with inflammatory bowel disease (IBD) is important during the ongoing coronavirus disease (COVID-19) pandemic. The administration of immunosuppressants in these patients remains controversial. Steroid doses adjustments are important to prevent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and subsequent COVID-19. Studies have shown that the administration of biological agents does not affect the severity of COVID-19. Clinicians should be aware that effective management of IBD during the pandemic must necessarily focus on strict control of intestinal inflammation to reduce the risk of SARS-CoV-2 infection. |