| Series | ||
|---|---|---|
| Title | A case of SSA/P (sessile serrated adenoma/polyp) with cytological dysplasia showing changes in endoscopic images over time | |
| Publish Date | 2020/11 | |
| Author | Bunichiro Kato | Department of Digestive Disease Center, Akita Red Cross Hospital |
| Author | Hiro-o Matsushita | Department of Digestive Disease Center, Akita Red Cross Hospital |
| Author | Kenjiro Yoshikawa | Department of Digestive Disease Center, Akita Red Cross Hospital |
| Author | Yoshihito Tanaka | Department of Digestive Disease Center, Akita Red Cross Hospital / Department of Molecular Diagnostic Pathology, Iwate Medical University, School of Medicine |
| Author | Tamotsu Sugai | Department of Molecular Diagnostic Pathology, Iwate Medical University, School of Medicine |
| Author | Takuo Tokairin | Department of Diagnostic Pathology, Akita Red Cross Hospital |
| Author | Katsuhiko Enomoto | Department of Diagnostic Pathology, Akita Red Cross Hospital |
| Author | Eiichiro Yamamoto | Department of Molecular Biology, Sapporo Medical University |
| Author | Hiromu Suzuki | Department of Molecular Biology, Sapporo Medical University |
| [ Summary ] | A woman in her 70s underwent lower gastrointestinal endoscopy in 2006, which revealed a flat elevated lesion (6 mm in diameter) with mucous caps at the hepatic flexure, and the patient was followed-up. Endoscopy performed in 2009 revealed a slightly elongated and enlarged glandular orifice on the left side of the lesion. This lesion appeared as a protruding mass (6 mm in diameter) on endoscopy performed in 2011. Magnifying endoscopy revealed a type II-open pit pattern on the right side of the mass and a type VI pit pattern extending from its apex to the left side. The endoscopic diagnosis was adenocarcinoma with sessile serrated adenoma/polyp (SSA/P) with depth of invasion classified as cTis. Endoscopic mucosal resection was performed, and histopathological examination of the resected specimen confirmed the diagnosis of SSA/P with cytological dysplasia. This case report would significantly contribute to the literature because we have presented the findings of close follow-up showing changes in endoscopic images over time in addition to the results of molecular biological analysis. | |