| Theme | Clinical characteristics of fecal immunochemical test (FIT) negative colorectal cancer | |
|---|---|---|
| Title | FIT-positive colorectal cancers versus FIT negative colorectal cancers: From the viewpoint of population-based screening | |
| Publish Date | 2019/09 | |
| Author | Kinichi Hotta | Division of Endoscopy, Shizuoka Cancer Center |
| Author | Takahisa Matsuda | Cancer Screening Center, National Cancer Center Hospital / Endoscopy Division, National Cancer Center Hospital / Division of Screening Technology, Center for Public Health Sciences, National Cancer Center |
| Author | Hiroaki Ikematsu | Department of Endoscopy, National Cancer Center Hospital East |
| Author | Yasuo Kakugawa | Cancer Screening Center, National Cancer Center Hospital / Endoscopy Division, National Cancer Center Hospital |
| Author | Kenichiro Imai | Division of Endoscopy, Shizuoka Cancer Center |
| Author | Sayo Ito | Division of Endoscopy, Shizuoka Cancer Center |
| Author | Toshio Uraoka | Department of Gastroenterology and Hepatology, Gunma University Graduate School of Medicine |
| Author | Yoshikatsu Koga | Exploratory Oncology Research & Clinical Trial Center, National Cancer Center |
| Author | Yutaka Saito | Endoscopy Division, National Cancer Center Hospital |
| [ Summary ] | The characteristics of fecal immunochemical test (FIT)-negative colorectal cancers (CRCs) were investigated based on the results of a populationbased screening trial using two-sample-FIT and total colonoscopy performed in Oshima, Tokyo. All FIT negative CRCs were intramucosal cancers and were completely treated by endoscopic resections. FIT-negative CRCs had the trend of early stage, right-sided, and flat type compared to the FIT positive CRCs. Development of new, effective, and organized screening methods combined FIT and colonoscopy are desired. | |