| Theme | Clinical characteristics of fecal immunochemical test (FIT) negative colorectal cancer | |
|---|---|---|
| Title | Colonoscopy after a negative fecal immunochemical test | |
| Publish Date | 2019/09 | |
| Author | Nozomu Kobayashi | Department of Gastroenterology, Tochigi Cancer Center |
| Author | Jun Konishi | Department of Gastroenterology, Tochigi Cancer Center |
| Author | Maki Konno | Department of Gastroenterology, Tochigi Cancer Center |
| [ Summary ] | The fecal immunochemical test (FIT) is an effective tool for colon cancer screening to select highrisk patients who need to undergo colonoscopy. However, approximately 20 % of colorectal cancers detected in patients who underwent screening showed negative FIT results. Direct screening colonoscopy is expected to identify such interval cancers missed by FIT; however, it may be less effective in screening low-risk patients. The Asia-Pacific Colorectal Screening scoring system was developed by The Asia-Pacific Working Group on Colorectal Cancer to identify individuals at a high risk for advanced neoplasms. This scoring system effectively identifi es high-risk patients with FIT-negative colon cancer to ensure timely colonoscopy in this selected population. Combination of FIT and colonoscopy is a useful screening tool (based on risk stratifi cation of patients) for more effective prevention of colorectal cancer deaths. | |