| Theme | Obscure gastrointestinal bleeding (OGIB) | |
|---|---|---|
| Title | Small intestinal bleeding in patients with hepatic disease | |
| Publish Date | 2019/08 | |
| Author | Shunji Fujimori | Division of Gastroenterology, Nippon Medical School Chiba Hokusoh Hospital / Department of Gastroenterology, Nippon Medical School, Graduate School of Medicine |
| Author | Airi Hoshimoto | Department of Gastroenterology, Nippon Medical School, Graduate School of Medicine |
| Author | Fumihiko Hashino | Department of Gastroenterology, Nippon Medical School, Graduate School of Medicine |
| Author | Hiroaki Kataoka | Department of Gastroenterology, Nippon Medical School, Graduate School of Medicine |
| Author | Takamitsu Umeda | Department of Gastroenterology, Nippon Medical School, Graduate School of Medicine |
| Author | Shinsuke Takagi | Department of Gastroenterology, Nippon Medical School, Graduate School of Medicine |
| Author | Takayoshi Nishimoto | Division of Gastroenterology, Nippon Medical School Chiba Hokusoh Hospital / Department of Gastroenterology, Nippon Medical School, Graduate School of Medicine |
| Author | Jun Omori | Department of Gastroenterology, Nippon Medical School, Graduate School of Medicine |
| Author | Katsuhiko Iwakiri | Department of Gastroenterology, Nippon Medical School, Graduate School of Medicine |
| [ Summary ] | Patients with liver cirrhosis are more likely to develop complications such as angioectasias, small intestinal varices, and/or a bleeding tendency. Therefore, small intestinal bleeding is strongly associated with liver cirrhosis. The occurrence of small intestinal angioectasias is 6-fold higher in patients with liver cirrhosis than in patients without liver cirrhosis. Notably, angioectasias are commonly detected in patients with liver cirrhosis. Moreover, patients with liver cirrhosis show an increased bleeding tendency. Reportedly, the rebleeding rate is 4-fold higher in patients with liver cirrhosis than in patients without liver cirrhosis. An association has been observed between portal hypertension and small intestinal edema. The prognosis of small intestinal bleeding in patients with liver cirrhosis is strongly associated with the severity of liver dysfunction. | |