| Theme | Metastatic recurrence and prognosis after endoscopic treatment for early colorectal carcinoma | |
|---|---|---|
| Title | Results and prognosis of the relapsed cases during the follow-up after endoscopic resection for T1 (SM) carcinomas | |
| Publish Date | 2019/06 | |
| Author | Yusuke Saitoh | Japanese Society for Cancer of the Colon and Rectum (JSCCR) project [Multicenter Study Regarding Metastasis and Recurrence after Endoscopic Resection for T1 (SM) Carcinomas] team members / Digestive Disease Center, Asahikawa City Hospital |
| Author | Shiro Oka | Japanese Society for Cancer of the Colon and Rectum (JSCCR) project [Multicenter Study Regarding Metastasis and Recurrence after Endoscopic Resection for T1 (SM) Carcinomas] team members |
| Author | Shinji Tanaka | Japanese Society for Cancer of the Colon and Rectum (JSCCR) project [Multicenter Study Regarding Metastasis and Recurrence after Endoscopic Resection for T1 (SM) Carcinomas] team members |
| Author | Yutaka Saito | Japanese Society for Cancer of the Colon and Rectum (JSCCR) project [Multicenter Study Regarding Metastasis and Recurrence after Endoscopic Resection for T1 (SM) Carcinomas] team members |
| Author | Hiroaki Ikematsu | Japanese Society for Cancer of the Colon and Rectum (JSCCR) project [Multicenter Study Regarding Metastasis and Recurrence after Endoscopic Resection for T1 (SM) Carcinomas] team members |
| Author | Masahiro Igarashi | Japanese Society for Cancer of the Colon and Rectum (JSCCR) project [Multicenter Study Regarding Metastasis and Recurrence after Endoscopic Resection for T1 (SM) Carcinomas] team members |
| Author | Yoshiki Wada | Japanese Society for Cancer of the Colon and Rectum (JSCCR) project [Multicenter Study Regarding Metastasis and Recurrence after Endoscopic Resection for T1 (SM) Carcinomas] team members |
| Author | Shin-ei Kudo | Japanese Society for Cancer of the Colon and Rectum (JSCCR) project [Multicenter Study Regarding Metastasis and Recurrence after Endoscopic Resection for T1 (SM) Carcinomas] team members |
| Author | Kiyonori Kobayashi | Japanese Society for Cancer of the Colon and Rectum (JSCCR) project [Multicenter Study Regarding Metastasis and Recurrence after Endoscopic Resection for T1 (SM) Carcinomas] team members |
| Author | Yuji Inoue | Japanese Society for Cancer of the Colon and Rectum (JSCCR) project [Multicenter Study Regarding Metastasis and Recurrence after Endoscopic Resection for T1 (SM) Carcinomas] team members |
| Author | Toshio Uraoka | Japanese Society for Cancer of the Colon and Rectum (JSCCR) project [Multicenter Study Regarding Metastasis and Recurrence after Endoscopic Resection for T1 (SM) Carcinomas] team members |
| Author | Hiroyasu Iishi | Japanese Society for Cancer of the Colon and Rectum (JSCCR) project [Multicenter Study Regarding Metastasis and Recurrence after Endoscopic Resection for T1 (SM) Carcinomas] team members |
| Author | Hiro-o Yamano | Japanese Society for Cancer of the Colon and Rectum (JSCCR) project [Multicenter Study Regarding Metastasis and Recurrence after Endoscopic Resection for T1 (SM) Carcinomas] team members |
| Author | Osamu Tsuruta | Japanese Society for Cancer of the Colon and Rectum (JSCCR) project [Multicenter Study Regarding Metastasis and Recurrence after Endoscopic Resection for T1 (SM) Carcinomas] team members |
| Author | Shinji Nagata | Japanese Society for Cancer of the Colon and Rectum (JSCCR) project [Multicenter Study Regarding Metastasis and Recurrence after Endoscopic Resection for T1 (SM) Carcinomas] team members |
| Author | Koichi Kurahara | Japanese Society for Cancer of the Colon and Rectum (JSCCR) project [Multicenter Study Regarding Metastasis and Recurrence after Endoscopic Resection for T1 (SM) Carcinomas] team members |
| Author | Yuichiro Yamaguchi | Japanese Society for Cancer of the Colon and Rectum (JSCCR) project [Multicenter Study Regarding Metastasis and Recurrence after Endoscopic Resection for T1 (SM) Carcinomas] team members |
| Author | Yasushi Sano | Japanese Society for Cancer of the Colon and Rectum (JSCCR) project [Multicenter Study Regarding Metastasis and Recurrence after Endoscopic Resection for T1 (SM) Carcinomas] team members |
| Author | Hiroshi Kashida | Japanese Society for Cancer of the Colon and Rectum (JSCCR) project [Multicenter Study Regarding Metastasis and Recurrence after Endoscopic Resection for T1 (SM) Carcinomas] team members |
| Author | Takahiro Horimatsu | Japanese Society for Cancer of the Colon and Rectum (JSCCR) project [Multicenter Study Regarding Metastasis and Recurrence after Endoscopic Resection for T1 (SM) Carcinomas] team members |
| Author | Shoichi Saito | Japanese Society for Cancer of the Colon and Rectum (JSCCR) project [Multicenter Study Regarding Metastasis and Recurrence after Endoscopic Resection for T1 (SM) Carcinomas] team members |
| Author | Hideki Ueno | Japanese Society for Cancer of the Colon and Rectum (JSCCR) project [Multicenter Study Regarding Metastasis and Recurrence after Endoscopic Resection for T1 (SM) Carcinomas] team members |
| Author | Megumi Ishiguro | Japanese Society for Cancer of the Colon and Rectum (JSCCR) project [Multicenter Study Regarding Metastasis and Recurrence after Endoscopic Resection for T1 (SM) Carcinomas] team members |
| Author | Hideki Ishikawa | Japanese Society for Cancer of the Colon and Rectum (JSCCR) project [Multicenter Study Regarding Metastasis and Recurrence after Endoscopic Resection for T1 (SM) Carcinomas] team members |
| Author | Yoichi Ajioka | Japanese Society for Cancer of the Colon and Rectum (JSCCR) project [Multicenter Study Regarding Metastasis and Recurrence after Endoscopic Resection for T1 (SM) Carcinomas] team members |
| Author | Yasuo Ohkura | Japanese Society for Cancer of the Colon and Rectum (JSCCR) project [Multicenter Study Regarding Metastasis and Recurrence after Endoscopic Resection for T1 (SM) Carcinomas] team members |
| Author | Takahiro Fujimori | Japanese Society for Cancer of the Colon and Rectum (JSCCR) project [Multicenter Study Regarding Metastasis and Recurrence after Endoscopic Resection for T1 (SM) Carcinomas] team members |
| Author | Toshiaki Watanabe | Japanese Society for Cancer of the Colon and Rectum (JSCCR) project [Multicenter Study Regarding Metastasis and Recurrence after Endoscopic Resection for T1 (SM) Carcinomas] team members |
| Author | Kenichi Sugihara | Japanese Society for Cancer of the Colon and Rectum (JSCCR) project [Multicenter Study Regarding Metastasis and Recurrence after Endoscopic Resection for T1 (SM) Carcinomas] team members |
| [ Summary ] | The recommendation for consideration of additional surgery after endoscopic resection for colorectal T1 (SM) carcinomas by JSCCR Guidelines is still controversial. The aim of this study was to elucidate the prognosis and the effectiveness of salvage therapy in patients with relapse or metastasis during the follow-up after endoscopic resection. A retrospective questionnaire survey was conducted for relapse cases during the period of 2001-2008. Results: 1) The total number of relapsed cases were 101. As for the relapse pattern, cases of lymph node metastasis were 21, those of distant metastases were 45, and those of local recurrences in the deeper part of the submucosal layer were 35. Cancer deaths were seen in 54 cases (60 %) among 90 follow-up relapse cases; for 50 % of these, the survival period was 39 months. 2) Prognosis was poor, regardless of the relapse pattern of lymph node metastasis, distant metastasis, and local recurrence of the deeper part of the submucosal layer. 3) The average survival period after relapse was significantly longer in patients with surgery for the relapsed disease compared with that in patients without surgery. Conclusion: As the prognosis was poor in relapse patients after endoscopic resection for T1 cancers, regardless of the relapse pattern, patients with risk factors for lymph node metastasis should be cautiously evaluated for follow-up after endoscopic resection without additional surgery. | |