| Theme | Metastatic recurrence and prognosis after endoscopic treatment for early colorectal carcinoma | |
|---|---|---|
| Title | Treatment strategy and risk factors of recurrence in superficial T1 colorectal cancer | |
| Publish Date | 2019/06 | |
| Author | Katsuro Ichimasa | Digestive Disease Center, Showa University Northern Yokohama Hospital |
| Author | Toyoki Kudo | Digestive Disease Center, Showa University Northern Yokohama Hospital |
| Author | Yuta Kouyama | Digestive Disease Center, Showa University Northern Yokohama Hospital |
| Author | Kenichi Mochizuki | Digestive Disease Center, Showa University Northern Yokohama Hospital |
| Author | Tomoyuki Ishigaki | Digestive Disease Center, Showa University Northern Yokohama Hospital |
| Author | Naoya Toyoshima | Digestive Disease Center, Showa University Northern Yokohama Hospital |
| Author | Yuichi Mori | Digestive Disease Center, Showa University Northern Yokohama Hospital |
| Author | Masashi Misawa | Digestive Disease Center, Showa University Northern Yokohama Hospital |
| Author | Takemasa Hayashi | Digestive Disease Center, Showa University Northern Yokohama Hospital |
| Author | Kunihiko Wakamura | Digestive Disease Center, Showa University Northern Yokohama Hospital |
| Author | Fumio Ishida | Digestive Disease Center, Showa University Northern Yokohama Hospital |
| Author | Shin-ei Kudo | Digestive Disease Center, Showa University Northern Yokohama Hospital |
| [ Summary ] | We reviewed 930 patients with resected T1 colorectal cancers (CRCs) between April 2001 and June 2015 at Showa University Northern Yokohama Hospital (mean follow-up, 52.3 months). Of these, 298 cases underwent endoscopic resection (ER) alone and 632 cases underwent surgical resection (SR). In the ER alone group, depressed-type morphology was a prognostic factor for recurrence (HR=80.47). Superficial-type T1 CRCs showed a higher rate of initial surgery (54.6 % vs. 24.3 %), vascular invasion (31.3 % vs. 20.3 %, P<0.001) and tumor budding (25.6 % vs. 17.8 %, P=0.01) than those of the protruded-type. All three superficial-type T1 CRCs with recurrence after ER were located in the rectum and two of these were depressed-type. Further research is required to reveal the characteristics of superficial-type, especially depressed-type T1 CRCs. | |