| Theme | Current topics in interval colorectal cancers | |
|---|---|---|
| Title | Interval cancer in view of the Japan Polyp Study | |
| Publish Date | 2017/01 | |
| Author | Takahisa Matsuda | Cancer Screening Center/Endoscopy Division, National Cancer Center Hospital |
| Author | Yasushi Sano | Sano Hospital |
| Author | Takahiro Fujii | TF Clinic |
| Author | the Japan Polyp Study Workgroup | the Japan Polyp Study Workgroup |
| [ Summary ] | It has been established that total colonoscopies (TCS) can reduce colorectal cancer mortality based on the results of several case-control/cohort studies. However, some authors have reported that the effects are less notable in the proximal colon than in the distal colon. Recently, interval cancer/post-colonoscopy colorectal cancer has attracted attention as an important cause of this condition. We assess the incidence and characteristics of lesions detected by TCS one-year after declaration of a "clean colon" based on the results of the Japan Polyp Study (JPS). As a result, it is suggested that overlooking nonpolypoid lesions, primarily LST-NG, in the proximal colon and small polypoid lesions in the distal colon may be the greatest causes of interval cancers. | |