INTESTINE Vol.21 No.1(1)

Theme Current topics in interval colorectal cancers
Title Concept, problems, and truth of "interval colorectal cancer"
Publish Date 2017/01
Author Hiro-o Yamano Department of Gastroenterology and Hepatology, Sapporo Medical University School of Medicine / Gastrointestinal Endoscopic Center, Sapporo Medical University Hospital / Digestive Desease Center, Akita Red Cross Hospital
Author Hiro-o Matsushita Digestive Desease Center, Akita Red Cross Hospital
Author Kenjiro Yoshikawa Digestive Desease Center, Akita Red Cross Hospital
Author Ryo Takagi Digestive Desease Center, Akita Red Cross Hospital
Author Eiji Harada Digestive Desease Center, Akita Red Cross Hospital
Author Yoshihito Tanaka Digestive Desease Center, Akita Red Cross Hospital / Department of Molecular Diagnostic Pathology, Department of Pathology, School of Medicine, Iwate Medical University
Author Yuko Yoshida Digestive Desease Center, Akita Red Cross Hospital
Author Kazunori Tsuda Digestive Desease Center, Akita Red Cross Hospital
Author Bun-ichiro Kato Digestive Desease Center, Akita Red Cross Hospital
Author Makoto Eizuka Department of Molecular Diagnostic Pathology, Department of Pathology, School of Medicine, Iwate Medical University
Author Tamotsu Sugai Department of Molecular Diagnostic Pathology, Department of Pathology, School of Medicine, Iwate Medical University
Author Eiichiro Yamamoto Department of Gastroenterology and Hepatology, Sapporo Medical University School of Medicine / Gastrointestinal Endoscopic Center, Sapporo Medical University Hospital / Department of Molecular Biology, Sapporo Medical University School of Medicine
Author Hiromu Suzuki Department of Molecular Biology, Sapporo Medical University School of Medicine
[ Summary ] Interval colorectal cancer (CRC) is defined as "Colorectal cancer after a screening or surveillance exam in which no cancer is detected, and before the date of the next recommended exam" by WEO (World Endoscopy Organization). As no determinate period has been set, interval CRC is defined as a group of cancers containing various uncertainties such as missed lesions, tumor growth speed, and quality of examination. However, we believe that the truth about interval CRC can be unrabeled by identifying the essence of rapidly growing cancer. Therefore, we judged that it is appropriate to analyze cancers cases where benign precursor lesions have undergone transformation into a deep submucosal cancer invasion in a short period. Herein, we present four cases treated at our center. We conclude that accumulation and analysys of such cases multiple institutions in the future would provide meaningful information.
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