INTESTINE Vol.20 No.6(2)

Theme Atypical cases of inflammatory bowel disease diagnosed with difficulty
Title Typical and atypical pathological findings and differential pathological diagnoses for inflammatory bowel disease
Publish Date 2016/11
Author Keisuke Ikeda Department of Pathology, Fukuoka University Chikushi Hospital
Author Akinori Iwashita Department of Pathology, Fukuoka University Chikushi Hospital
Author Hiroshi Tanabe Department of Pathology, Fukuoka University Chikushi Hospital
Author Atsuko Ota Department of Pathology, Fukuoka University Chikushi Hospital
[ Summary ] Pathological features and methods for discriminating CD from UC are examined, as well as the major differential diagnoses for both diseases. Differential diagnoses of the primary factors concerning CD and UC are summarized. The three salient points are the presence or absence of epithelioid cell granuloma, focal or diffuse inflammation, and observation of normal or nearly normal mucosa as well as nonatrophic crypts in the active phase. When a diagnosis is difficult to achieve for IBD atypical cases, it is necessary to compare those findings to those of typical cases. Examination of clinical information and pathology results is essential to produce correct diagnoses.
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