| Theme | "Early Colorectal Cancer" and "Intestine", Road to future | |
|---|---|---|
| Title | Translational research-based approaches for the gastrointestinal tract | |
| Publish Date | 2016/01 | |
| Author | Hiro-o Yamano | Digestive Desease Center, Akita Red Cross Hospital |
| Author | Hiro-o Matsushita | Digestive Desease Center, Akita Red Cross Hospital |
| Author | Kenjiro Yoshikawa | Digestive Desease Center, Akita Red Cross Hospital |
| Author | Eiji Harada | Digestive Desease Center, Akita Red Cross Hospital |
| Author | Yoshihito Tanaka | Digestive Desease Center, Akita Red Cross Hospital |
| Author | Michiko Nakaoka | Digestive Desease Center, Akita Red Cross Hospital |
| Author | Yuko Yoshida | Digestive Desease Center, Akita Red Cross Hospital |
| Author | Tamotsu Sugai | Department of Molecular Diagnostic Pathology, Department of Pathology, School of Medicine, Iwate Medical University |
| Author | Eiichiro Yamamoto | Department of Molecular Biology, Sapporo Medical University School of Medicine |
| Author | Hiromu Suzuki | Department of Molecular Biology, Sapporo Medical University School of Medicine |
| [ Summary ] | Translational research (TR) is aimed at efficiently and effectively translating the findings of basic research from different industries into practical use in clinical medicine. Herein, we performed TR on serrated lesions, which have unknown clinicopathological features. We found correlations among the magnified endoscopic findings, pathological features, and molecular biological analysis results of sessile serrated adenoma/polyp (SSA/P) and other lesions belonging to their family. During the course of our study, we also faced new problems and challenges. TR is speculated to aid in elucidating the pathogenesis of gastrointestinal lesions and to contribute greatly in areas right from the diagnosis through the treatment in the next few decades. Moreover, it is speculated to aid in the diagnosis of digestive tract diseases in the future. | |