| Theme | "Early Colorectal Cancer" and "Intestine", Road to future | |
|---|---|---|
| Title | Magnifying chromoendoscopy─from pit pattern diagnosis to endocytoscopy | |
| Publish Date | 2016/01 | |
| Author | Yuichi Mori | Digestive Disease Center, Showa University Northern Yokohama Hospital |
| Author | Shin-ei Kudo | Digestive Disease Center, Showa University Northern Yokohama Hospital |
| Author | Kunihiko Wakamura | Digestive Disease Center, Showa University Northern Yokohama Hospital |
| Author | Masashi Misawa | Digestive Disease Center, Showa University Northern Yokohama Hospital |
| Author | Toyoki Kudo | Digestive Disease Center, Showa University Northern Yokohama Hospital |
| Author | Takemasa Hayashi | Digestive Disease Center, Showa University Northern Yokohama Hospital |
| Author | Hideyuki Miyachi | Digestive Disease Center, Showa University Northern Yokohama Hospital |
| Author | Atsushi Katagiri | Digestive Disease Center, Showa University Northern Yokohama Hospital |
| Author | Fumio Ishida | Digestive Disease Center, Showa University Northern Yokohama Hospital |
| [ Summary ] | Magnifying chromoendoscopy provides for objective diagnoses by focusing on pit structures in the superficial layer of the colonic mucosa, thus helping to develop accurate pathological predictions of target lesions. Therefore, this technique is considered to provide additional diagnostic value to normal endoscopic diagnosis which is sometimes subjective and depends on the endoscopist's experience. Owing to intensive discussion of magnifying chromoendoscopy over the past 20 years, pit pattern diagnosis has become recognized as a useful diagnostic tool which has become widely implemented worldwide. Endocytoscopy, using ultra-magnification of 450 power is a newly developed endoscopic technique. This approach facilitates observation of not only structural atypia but also cellular atypia associated with tumors, which could not be achieved through previous pit pattern diagnoses. Compared to other emerging endoscopic modalities, endocytoscopy has the potential to realize the goal of being accepted as a form of "genuine optical biopsy". Thus, its usefulness in clinical practice is expected to be realized in the near future. | |