| Theme | "Laterally spreading tumor" of the large intestine | |
|---|---|---|
| Title | The clinical significance of laterally spreading tumor of the colon and rectum-the unique featurcs of clinicopathological study | |
| Publish Date | 1998/09 | |
| Author | Takeshi Terai | Department of Gastroenterology, Juntendo University, School of Medicine |
| [ Summary ] | Recently, the term "laterally spreading tumor (LST)" has been used by many colonoscopists without definite concept in mind. However there are some objections about the terminology and the concepts concerning this type of tumor. We analyzed the clinicopathological findings of laterally spreading tumors by comparing I s and IIa typed tumors to evaluate whether laterally spreading tumors have specific features and may be classified as an independent disease entity. One hundred and seventy six LST, 134 I s typed tumors, and 47 IIa typed tumors of a size greater than 10mm were studied. LSTs were divided into the 77 LST-granular type category (LSTG) with a granular surface and the 99 LST-non granular type category (LSTNG) without a granular surface. By statistical evaluation, LSTGs displayed a significant difference in size and location compared to I s or IIa typed tumors. There were no significant difference between the cancer rate for LSTGs and that for I s or IIa typed tumors, although LSTGs with the giant nodules have a significantly higher cancer rate (70.0%) than I s or IIa typed tumors. On the other hand, there were no significant difference of size or location between LSTNGs and I s or IIa typed tumors. However LSTNGs have a significantly higher cancer rate (52.5%) than I s or IIa typed tumors. Nevertheless, there were some cases which were barely classified as LSTGs or LSTNGs because their tumor surfaces had both components, a granular surface and a non granular surface. Summarizing these results, we concluded that there are several types of clinicopathological evidence which support the concept that LSTs should be classified as an independent disease entity. Whether LSTNGs should be regarded as the same disease entity as LSTGs should be further discussed. |
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