INTESTINE Vol.19 No.6(2)

Theme Cytomegalovirus enterocolitis and Clostridium difficile infection
Title Clinical symptoms and endoscopic findings of cytomegalovirus enterocolitis
Publish Date 2015/11
Author Kiyotaka Okawa Department of Gasteoenterology, Osaka City Juso Hospital
Author Tetsuya Aoki Department of Gasteoenterology, Osaka City Juso Hospital
Author Wataru Ueda Department of Gasteoenterology, Osaka City Juso Hospital
Author Hiroko Ohba Department of Gasteoenterology, Osaka City Juso Hospital
Author Masato Miyano Department of Gasteoenterology, Osaka City Juso Hospital
Author Hideki Fujii Department of Gasteoenterology, Osaka City Juso Hospital
Author Seiko Yamaguchi Department of Gasteoenterology, Osaka City Juso Hospital
Author Osamu Kurai Department of Gasteoenterology, Osaka City Juso Hospital
Author Koji Sano Department of Gastroenterology, Osaka City General Hospital
[ Summary ] We compared the clinical symptoms and endoscopic findings of 40 patients with cytomegalovirus (CMV) enterocolitis and conducted a literature review. Patients with CMV enterocolitis could be categorized into the following three main groups : patients with acquired immune deficiency syndrome (AIDS) (9), patients with drug-induced immunodeficiency (20), and patients with immunocompetence (11). Diarrhea is the most frequent symptom in patients with AIDS, and bleeding is most frequent in patients with drug-induced immunodeficiency. Patients with CMV enteritis exhibited massive bleeding and abdominal pain. In contrast, patients with CMV colitis primarily had diarrhea and bleeding. The rate of emergency operation for CMV enteritis is significantly higher than that for CMV colitis. No correlation was found between rectal lesion and bleeding in patients with CMV enterocolitis. Endoscopic findings of CMV enterocolitis include not only round ulcers but also various ulcers. There were no cases of CMV enterocolitis developed infl ammatory mucosa without ulcers.
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