| Theme | Cytomegalovirus enterocolitis and Clostridium difficile infection | |
|---|---|---|
| Title | Infection and pathophysiology of cytomegalovirus | |
| Publish Date | 2015/11 | |
| Author | Takashi Fujiwara | Department of Gastroenterology, Tokyo Metropolitan Cancer and Infectious Disease Center Komagome Hospital |
| Author | Kouichi Koizumi | Department of Gastroenterology, Tokyo Metropolitan Cancer and Infectious Disease Center Komagome Hospital |
| Author | Junko Fujiwara | Department of Endoscopy, Tokyo Metropolitan Cancer and Infectious Disease Center Komagome Hospital |
| Author | Taku Tabata | Department of Endoscopy, Tokyo Metropolitan Cancer and Infectious Disease Center Komagome Hospital |
| Author | Go Kuwata | Department of Gastroenterology, Tokyo Metropolitan Cancer and Infectious Disease Center Komagome Hospital |
| [ Summary ] | Cytomegalovirus (CMV) has an escape mechanism from the immunoresponse of the host. CMV infection is characteristically a latent infection. CD8-positive T cells production is the most important immunoresponse of the host against CMV, and CMV is reactivated by cellular immunity suppression. CMV infection commonly occurs in the gastrointes tinal tract. Erosions and ulcers are observed in CMV enterocolitis. Ulceration is regarded as an ischemic change. | |