| Theme | <Comprehensible explanation> "JGES guidelines for colorectal endoscopic submucosal dissection/endoscopic mucosal resection" | |
|---|---|---|
| Title | Handling of resected specimens and pathological evaluation of curability | |
| Publish Date | 2015/09 | |
| Author | Takashi Yao | Department of Human Pathology, Juntendo University Graduate School of Medicine |
| [ Summary ] | Accurate pathological diagnosis of lesions resected using endoscopic mucosal resection (EMR) or endoscopic submucosal dissection (ESD) is essential for evaluation of curability, and adequate handling of the resected specimen is necessary, including observation, fixation, and cutting of the specimen. Pathological diagnosis is carried out in accordance with the Japanese Classification of Colorectal Carcinoma (8th edition). In order to determine curability, the evaluation of resected margin, histological type, depth of invasion, lymphovascular invasion, and tumor budding is particularly important. Since pathological factors can be affected by various artifacts and determination of lymphovascular invasion may not be complete even when using special staining, determining the curability of the lesion only on the basis of the pathology report is insufficient. Before arriving at the final decision, it is important to consider consistency with the clinical findings. |
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