| Theme | Inflammation and cancer in the lower GI tract | |
|---|---|---|
| Title | Treatment of inflammatory cancers : Prospects for treatment and prevention in internal medicine | |
| Publish Date | 2015/07 | |
| Author | Kazutomo Yamasaki | Department of Gastroenterology, Fukuoka University Chikushi Hoptipal |
| Author | Humihito Hirai | Department of Gastroenterology, Fukuoka University Chikushi Hoptipal |
| Author | Takashi Hisabe | Department of Gastroenterology, Fukuoka University Chikushi Hoptipal |
| Author | Toshiyuki Matsui | Department of Gastroenterology, Fukuoka University Chikushi Hoptipal |
| [ Summary ] | Increases in disease incidence and prolonged cases of inflammatory bowel diseases (IBDs) such as ulcerative colitis (UC) and Crohn's disease (CD) have led to an increase in cancer complications. Chemopreventive drugs have recently garnered attention in the United States, with various reports on the cancer preventative effects of 5-aminosalicylic acid and thiopurine, drugs typically used to treat inflammatory disease. As prolonged chronic inflammation is a risk factor for cancer complications, these drugs may help prevent cancer onset through longterm maintenance of remission. | |