| Theme | Colonoscopy for the super-elderly | |
|---|---|---|
| Title | Characteristics of colorectal cancer occurring in elderly patients：pathological viewpoint | |
| Publish Date | 2015/01 | |
| Author | Tomio Arai | Department of Pathology, Tokyo Metropolitan Geriatric Hospital |
| Author | Yoko Matsuda | Department of Pathology, Tokyo Metropolitan Geriatric Hospital |
| Author | Hideki Hamayasu | Department of Pathology, Tokyo Metropolitan Geriatric Hospital |
| Author | Fukuo Kondo | Department of Diagnostic Pathology, Teikyo University Hospital |
| Author | Naoko Honma | Research Team for Geriatric Pathology, Tokyo Metropolitan Institute of Gerontology |
| Author | Junko Aida | Research Team for Geriatric Pathology, Tokyo Metropolitan Institute of Gerontology |
| Author | Kaiyo Takubo | Research Team for Geriatric Pathology, Tokyo Metropolitan Institute of Gerontology |
| [ Summary ] | A proximal shift is the most characteristic feature in very old patients with colorectal cancer (CRC). In elderly female patients aged 85 or older, approximately 60 % of CRCs occur in the proximal colon. Regarding histological subtype, the number of poorly differentiated adenocarcinomas including medullary carcinomas and mucinous carcinomas tends to increase with patient age. Approximately 5 to 7 % of elderly CRC patients aged 85 years or older have multiple cancers in the large bowel, and approximately one-third have extra-colorectal malignancies. Sessile serrated adenoma/polyps (SSA/P) are thought to be precursor lesions for medullary carcinomas which form in elderly patients. | |