| Theme | Intestinal Behçet's disease and simple ulcer of the intestine | |
|---|---|---|
| Title | Upper gastrointestinal involvement in patients with Behçet's disease and simple ulcers | |
| Publish Date | 2014/11 | |
| Author | Yasuhiro Takaki | Department of Gastroenterology, Fukuoka University Chikushi Hospital |
| Author | Shigeyoshi Yasukawa | Department of Gastroenterology, Fukuoka University Chikushi Hospital |
| Author | Fumihito Hirai | Department of Gastroenterology, Fukuoka University Chikushi Hospital |
| Author | Yutaka Yano | Department of Gastroenterology, Fukuoka University Chikushi Hospital |
| Author | Takashi Hisabe | Department of Gastroenterology, Fukuoka University Chikushi Hospital |
| Author | Toshiyuki Matsui | Department of Gastroenterology, Fukuoka University Chikushi Hospital |
| Author | Akinori Iwashita | Department of Pathology, Fukuoka University Chikushi Hospital |
| Author | Keisuke Ikeda | Department of Pathology, Fukuoka University Chikushi Hospital |
| Author | Hiroshi Tanabe | Department of Pathology, Fukuoka University Chikushi Hospital |
| Author | Kitarou Futami | Department of Surgery, Fukuoka University Chikushi Hospital |
| [ Summary ] | The most frequent site of gastrointestinal involvement in patients with Behçet's disease (BD) and simple ulcer (SU) is ileocecal region, and the most common manifestation of these lesion is deep punched-out ulcers. On the other hand, it is known that upper gastrointestinal involvement occurs in a small number of patients with BD and SU. Accordingly, we summarized the characteristics of upper gastrointestinal lesions in patients with intestinal BD and SU by reviewing the clinical findings of our own cases and those provided in medical literature. The prevalence of esophageal involvement was ranged from 6.7 % to 18.5 %. The most characteristic manifestation in the esophagus was round or oval shaped solitary or multiple ulcers which resembled the typical ileocecal ulcers. In addition, some cases revealed the gastroduodenal involvement. However, it is not clear whether or not gastroduodenal lesions are specific to BD and SU because comorbid Helicobacter pylori infections and/or drug induced mucosal injury can be the cause of such lesions. | |