| Theme | Intestinal Behçet's disease and simple ulcer of the intestine | |
|---|---|---|
| Title | A distinction between intestinal Behçet's disease and simple ulcer | |
| Publish Date | 2014/11 | |
| Author | Kazuki Kakimoto | Second Department of Internal Medicine, Osaka Medical College |
| Author | Mitsuyuki Murano | Murano Clinic |
| Author | Takuya Inoue | Second Department of Internal Medicine, Osaka Medical College |
| Author | Yosuke Abe | Second Department of Internal Medicine, Osaka Medical College |
| Author | Ken Kawakami | Second Department of Internal Medicine, Osaka Medical College |
| Author | Toshihiko Okada | Second Department of Internal Medicine, Osaka Medical College |
| Author | Sadaharu Nouda | Second Department of Internal Medicine, Osaka Medical College |
| Author | Naoko Murano | Murano Clinic |
| Author | Kazuhide Higuchi | Second Department of Internal Medicine, Osaka Medical College |
| [ Summary ] | To clarify the differences between intestinal Behçet's disease (intestinal BD) and simple ulcer (SU), we reviewed the clinical presentation, clinical course, endoscopic findings, and therapeutic aspects for 29 patients with intestinal BD and 18 patients with SU. Patients with intestinal BD were further classified as having complete BD or incomplete BD according to clinical symptoms. Among patients with SU, those with oral aphthae were included in the SU(+) group and those without oral aphthae were included in the SU(-) group. No patient in the SU(-) group demonstrated disease escalation during the clinical course；however, four patients in the SU(+) group demonstrated escalation to incomplete BD, and one patient with incomplete BD demonstrated escalation to complete BD. In the SU(+) group, 37.5 % of patients had gastrointestinal lesions outside the ileocecal region, whereas no patient in the SU(-) group had lesions outside the ileocecal region. Both the surgery rate and the rate of recurrence were lower in the SU(-) group than in the SU(+) and intestinal BD groups. Thus, the pathology of the disorder may differ according to the presence of oral aphthae. | |