| Theme | Differential diagnosis for common enterocolitis, especially in endoscopic findings | |
|---|---|---|
| Title | Antibiotic-associated acute hemorrhagic colitis | |
| Publish Date | 2014/07 | |
| Author | Shiro Nakamura | Division of Inflammatory Bowel Disease, Department of Internal Medicine, Hyogo College of Medicine |
| Author | Nobuyuki Hida | Division of Inflammatory Bowel Disease, Department of Internal Medicine, Hyogo College of Medicine |
| Author | Masaki Iimuro | Division of Inflammatory Bowel Disease, Department of Internal Medicine, Hyogo College of Medicine |
| Author | Takako Miyazaki | Division of Inflammatory Bowel Disease, Department of Internal Medicine, Hyogo College of Medicine |
| Author | Yoko Yokoyama | Division of Inflammatory Bowel Disease, Department of Internal Medicine, Hyogo College of Medicine |
| Author | Koji Kamikozuru | Division of Inflammatory Bowel Disease, Department of Internal Medicine, Hyogo College of Medicine |
| Author | Misaki Nakamura | Division of Inflammatory Bowel Disease, Department of Internal Medicine, Hyogo College of Medicine |
| Author | Junsuke Oku | Division of Inflammatory Bowel Disease, Department of Internal Medicine, Hyogo College of Medicine |
| Author | Mikio Kawai | Division of Inflammatory Bowel Disease, Department of Internal Medicine, Hyogo College of Medicine |
| [ Summary ] | Antibiotic-associated acute hemorrhagic colitis presents with the sudden onset of abdominal pain and bloody diarrhea several days after antibiotic administration. Diffuse segmental intramucosal hemorrhaging and red edematous lesions can be observed, primarily from the descending to the transverse colon. The course is self-limiting, and symptoms abate shortly after discontinuation of the offending antibiotic. Penicillin derivatives are the most common causative agent, and the etiology, while unclear, is most likely associated with allergic and microbial substitutions particularly those involving Klebsiella oxytoca. | |