INTESTINE Vol.17 No.4(5)

Series
Title Case of 0-IIa + IIc (NPG) submucosal invasive carcinoma 15 mm in diameter transformed from 0-Is minute polyp 3 mm in diameter over 7 years
Publish Date 2013/08
Author Motomi Terasaki Department of Endoscopy, Hiroshima University
Author Shinji Tanaka Department of Endoscopy, Hiroshima University
Author Hiroyuki Kanao Department of Endoscopy, Hiroshima University
Author Shiro Oka Department of Endoscopy, Hiroshima University
Author Kazuaki Chayama Department of Gastroenterology and Metabolism, Hiroshima University
[ Summary ] A man in his sixties had been pointed out sessile PG type polyp in the sigmoid colon 3 mm in diameter in February 2005 and in February 2007. Due to the patient's personal circumstances, he had not been followed-up after the second observation. He had a colonoscopy for the examination of the cause of his left lower abdominal pain in June 2012 (7 years and 4 months after the first observation). Standard colonoscopy exhibited a NPG type 0-IIa + IIc submucosal invasive carcinoma 15 mm in diameter in the sigmoid colon. This was the same region where a 3 mm 0-Ⅰs polyp was detected 7 years previously. A laparoscopic assisted colectomy was performed. Histologic findings of the resected specimen revealed a NPG type moderately differentiated adenocarcinoma with deep submucosal invasion (2,600μm). This case is very interesting in terms of the morphological progression of colorectal cancer.
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