| Theme | Ulcerative lesions in the ileocecal region | |
|---|---|---|
| Title | Defining intestinal Behçet's disease and simple ulcer : the different entities ? | |
| Publish Date | 2013/08 | |
| Author | Yasuhiro Takaki | Department of Gastroenterology, Fukuoka University Chikushi Hospital |
| Author | Fumihito Hirai | Department of Gastroenterology, Fukuoka University Chikushi Hospital |
| Author | Yutaka Yano | Department of Gastroenterology, Fukuoka University Chikushi Hospital |
| Author | Akihiro Koga | Department of Gastroenterology, Fukuoka University Chikushi Hospital |
| Author | Keiichiro Matsumura | Department of Gastroenterology, Fukuoka University Chikushi Hospital |
| Author | Takashi Nagahama | Department of Gastroenterology, Fukuoka University Chikushi Hospital |
| Author | Takashi Hisabe | Department of Gastroenterology, Fukuoka University Chikushi Hospital |
| Author | Toshiyuki Matsui | Department of Gastroenterology, Fukuoka University Chikushi Hospital |
| Author | Akinori Iwashita | Department of Pathology, Fukuoka University Chikushi Hospital |
| Author | Seiji Haraoka | Department of Pathology, Fukuoka University Chikushi Hospital |
| Author | Keisuke Ikeda | Department of Pathology, Fukuoka University Chikushi Hospital |
| Author | Hiroshi Tanabe | Department of Pathology, Fukuoka University Chikushi Hospital |
| Author | Kitaro Futami | Department of Surgery, Fukuoka University Chikushi Hospital |
| Author | Takafumi Maekawa | Department of Surgery, Fukuoka University Chikushi Hospital |
| [ Summary ] | There were 27 cases which were diagnosed as being simple ulcers or Behçet's disease. They were divided into three groups : definite Behçet's disease (DBD), suspected Behçet's disease (SBD), and non-Behçet's disease (NBD). We organized the frequency, location and type of gastrointestinal involvement, and clinical course into respective groups. The results were as follows : (1) frequencies of the three groups were：5 cases in the NBD group (19 %), 12 cases in the SBD group (44 %), 10 cases in the DBD group (37 %). The frequency of the NBD group was the lowest. (2) rates of typical lesions in the ileocecal region were high in all the three groups. However, 80 % of the lesions in NBD cases were located only in the ileocecal region, whereas the rates of lesions limited to the ileocecal regions in the SBD and DBD groups were 42 % and 30 %, respectively. In cases of the SBD and DBD groups, lesions were frequently found in the esophagus, ileum and colon. (3) manifestations of Behçet's disease were not observed in the NBD group. Disease stage progression was seen in one patient with SBD and one with DBD. (4) surgical operations were performed in three cases (60 %) in the NBD group. All of these three patients underwent subsequent operations. Nine cases (41 %) in the SBD/DBD group underwent surgical procedures. 56 % of those nine cases underwent subsequent operations. In relation to the above information, the following ideas are suggested : the frequency of ileocecal lesions in all three groups was high. However, cases in the NBD group exhibited symptoms of Behçet's disease, which occured rarely and were limited to the ileocecal region. On the other hand, some cases in the SBD/DBD group displayed disease stage progression. The NBD group and the SBD/DBD group may exhibit different disease characteristics. |
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