INTESTINE Vol.16 No.6(2-1)

Theme How should we interpret sessile serrated adenoma/polyp ?
Title Detection and diagnosis of SSA/P using standard colonoscopy
Publish Date 2012/11
Author Takahiro Fujii Takahiro Fujii Clinic
Author Takahiro Fujimori Department of Pathology, Dokkyo Medical University
[ Summary ] Of the 2261 serrated lesions including hyperplastic polyps (HPs) examined, sessile serrated adenomas/polyp (SSA/Ps) were found in 199 lesions (8.8 %). In addition, of the 245 serrated lesions measuring 10 mm or greater examined, excluding traditional serrated adenomas (TSAs), large hyperplastic polyps (LHPs) and SSA/Ps were found in 95 (38.8 %) as well as 150 (61.2 %) lesions, respectively. This suggests that LHPs and SSA/Ps may constitute identical pathological entities based on the JSCCR criteria for histological diagnosis of serrated lesions. However, LHPs and SSA/Ps do not lend themselves to differential diagnosis with conventional colonoscopy. This suggests they do not differ greatly in macroscopic terms, while Is or Is + IIa are more frequently associated with SSA/Ps than with LHPs. It is therefore suggested that it is critically important to focus attention on lesions covering the mucus in the right colon. Narrow-band imaging (NBI)-based observation may be useful, in the detection and differentiation of these lesions.
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