INTESTINE Vol.16 No.5(2-1)

Theme Intestinal ulcerations related to vascular disorders
Title Endoscopic findings for intestinal amyloidosis
Publish Date 2012/09
Author Koichi Kurahara Division of Gastroenterology, Matsuyama Red Cross Hospital
Author Yumi Oshiro Department of Pathology, Matsuyama Red Cross Hospital
Author Tetsushi Kudo Department of Internal Medicine, Kyushu Central Hospital of the Mutual Aid Association of Public School Teachers
Author Yuka Matsumoto Division of Gastroenterology, Matsuyama Red Cross Hospital
Author Keisuke Kawasaki Division of Gastroenterology, Matsuyama Red Cross Hospital
Author Kazuoki Hizawa Department of Internal Medicine, Kyushu Central Hospital of the Mutual Aid Association of Public School Teachers
Author Hiroyuki Kobayashi Division of Gastroenterology, Matsuyama Red Cross Hospital
Author Takayuki Matsumoto Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University
Author Tadahiko Fuchigami Division of Gastroenterology, Matsuyama Red Cross Hospital
[ Summary ] Endoscopic findings in the small intestine and colon have revealed considerable differences between amyloid type AA and AL proteins. In cases involving AA amyloidosis, a mucosal pattern with numerous fine granular elevations is evident. This correlates with expansion of amyloid deposits in the lamina propria. Patients with AL amyloidosis, exhibit polypoid protrusions and thickening of the folds, reflecting massive amyloid deposits in the muscularis mucosa, submucosa and muscularis propria. Recently, ulceration and submucosal hematoma of the intestine have been reported in patients with AL amyloidosis.
back